The star has given the entirety of his twenty-five thousand pound honor cash to the trust for venues, which works to protect the UK's small concert spaces.
The star was presented with the cheque on mid-October as his latest record People Watching was declared the outstanding release of the previous year.
The musician has decided to give the cash to the MVT, in appreciation of the essential function local spots had in his beginning days.
"As an artist would not have achieved this success if it weren't for all the performances I did around the North East, and further afield, when I was just getting going," said Fender. "These spaces are renowned, but they are in difficulty."
From early 2023 onward, at least 150 of these locations have shut down – approximately one-sixth of the whole industry in the UK.
In the last year, top acts including Pulp, Coldplay, the singer Katy Perry and Ed Sheeran have all supported the Music Venues Trust in its initiatives to help venues survive, by applying a modest fee to their ticket costs, which supports independent venues.
He also participated, collecting more than £100,000 on his 2024 arena tour to support thirty-eight local spots across Britain.
These funds supported venues that were dealing with imminent closure due to issues arising from flooding, blazes and bereavements, as well as regulatory hurdles, legal disputes and noise complaints.
Some locations obtained funding support in upgrading amenities and sound and lighting systems that directly benefitted artists and fans.
"The idea that funds from shows in big venues helps the smaller venues, where it all starts for musicians like me, is just sensible," Sam Fender has commented.
The musician is not the first artist to donate his Mercury Prize winnings to worthy causes.
Back when they received the prize in 1996 for their record Different Class, lead singer Cocker declared that the band would give their winnings to the charity War Child.
During 2002, musician the artist split her bounty across a few organizations, such as the children's charity and a Sickle Cell charity.
"And I donated a grand to the center, to their gymnastics class, because I trained in gymnastics when I was younger and they needed new equipment," she explained to outlets.
In recent years, they donated their winnings to the youth organization that supported their band, in addition to other grassroots music organisations.
And winners that year they donated their award to a MS organization after a acquaintance was identified with the condition.
"Winning was quite enough," remarked vocalist the singer. "The money was the extra but we didn't require the extra, because we had the cake. So our victory impacted the lives of others."
In the past week, the Music Venues Trust revealed it had saved several local spots in the South East, by placing them under community ownership.
One venue in that area and the second in the city were acquired under the community ownership scheme, which is backed by a national body and supporters who purchase "ownership units" in the properties.